They explored greater tubular occlusion potential and more acid resistance of Pro-argin in comparison to FCPS after subsequent seven days of application on dentinal discs [38]. Yes, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste should be used for twice daily toothbrushing to provide ongoing relief from the pain of sensitive teeth. *with direct application and daily brushing. HOW DOES Colgate SENSITIVE INSTANT Relief Repair & Prevent WORK? The maximum sampling time was 15min. Clinical Efficacy Of BioMin F, Colgate Sensitive Pro-Relief And Sensodyne Rapid Action Dentifrices In DH The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. After six weeks, FCPS-based dentifrices showed greater clinical efficacy with mean scores (1.801.73) than other treatment arms for waterjet stimulated DH. The burden of dentine hypersensitivity. Comparative efficacy of BioMin-F, Colgate Sensitive Pro-relief and Sensodyne Rapid Action in relieving dentin hypersensitivity: a randomized controlled trial, https://doi.org/10.1186/s12903-021-01864-x, https://clinicaltrials.gov/ct2/show/NCT04249336, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. 4.4 5 0 198 198 Colgate Sensitive Pro-Relief Gum Therapy toothpaste helps instantly repair sensitive teeth and provides lasting protection against hypersensitivity. Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG. Cunha-Cruz J, Wataha JC. Gentle whitening formula. FCPS was incorporated in OTC dentifrice with calcium, low contents of fluoride, and high contents of phosphate ions. J Oral Sci. Our study included an Asian population, and most of the published literature was associated with the Caucasian population. Therefore, it was considered to be rejected at a p valueof 0.05. 1,2 According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. 2016;36(3):4403. statement and Madurai: Best Dental Science College; 2020. YYYY Colgate-Palmolive Company. found the clinical efficacy of Pro-argin better than strontium acetate for mechanical and air-blast stimulated DH on VAS and SCASS in follow-up periods of one minute, three days, two, four and eight weeks in a systematic review in 2015. Nathoo S, Delgado E, Zhang YP, DeVizio W, Cummins D, Mateo LR: Comparing the efficacy in providing instant relief of dentine hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride and to a control toothpaste with 1450 ppm fluoride: A three-day clinical study in New Jersey, USA. However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. Then, the repeated measure was obtained after five minutes for previous pain recovery, and dentifrices were provided to the patient for self-application. Dentine hypersensitivity (DH) is a chronic condition with acute, transient pain in non-carious teeth that originates in response to thermal stimuli such as hot or cold, chemicals like acidic or sweet or salt, and mechanical stimuli due to exposure to dentinal tubules without any apparent clinical disease [1]. Plus it has the freshness you trust from Colgate! 1). Table 2 presents descriptive statistics of the primary analysis population as the primary statistical analysis was performed for 47 males and 81 females of age ranging from 18 to 50years with a mean age of 34.18.9. J Dent Res. Arshad, S., Zaidi, S.J.A. There was no statistically significant treatment difference between the two (p=0.499). The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Ingredients *Calcium carbonate *Water 1. Anvnd tv gnger dagligen. Tandkrmen har ett slipmedel som ger en mild polering och tar bort yttre flckar och fluor skyddar tnderna mot karies. was used for statistical analysis. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. A toothbrushing demonstration model from Nissin Company specification [PE-ORT002] was used to explain to the study participants about applying OTC dentifrices for one minute with the participant's finger. No side effects, apart from money not well spent. PubMedGoogle Scholar. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Patel VR, Shettar L, Thakur S, Gillam D, Kamala DN. Ingredients *Potassium Nitrate Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). Colgate Sensitive PRO-Relief provides you relief from sudden shocks of pain and long-term sensitivity with regular use. Researchers have investigated the clinical efficacy of popular propriety occluding dentifrices containing Pro-argin, strontium acetate, and FCPS formulations for treating DH and have found no adverse effects. Statistical Package for the Social Sciences software v.21.0. Pro-argin resulted in the immediate treatment response and statistically significant (p<0.001) clinical reduction in DH than FCPS in the present study, as shown in Table 3. Int J Dent. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. These dentifrices were extracted in a plain tube by the dental assistant from commercial packing and labelled with treatment codes to keep the principal investigator and participants blinded at the time of treatment assignment. 2016;3(1):0504. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. Size: 75ml (Approx.) Though all bioactive agents have a significant treatment effect in reducing DH, there is currently no consensus on the unequivocal efficacy of any product or bioactive agent used for managing the condition due to huge variations and heterogeneity in the conduct of clinical trials on DH [6]. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. More robust trials with a large number of participants are recommended for furtherassessing the impact of DH on the oral health-related quality of life and the difference in the effectiveness of treatments. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. The benefits are backed by over a decade of clinical research, summarized as follows. Colgate-Palmolive Company 2018. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. These then interact to form a complex with positive charge. J Clin Dent. Colgate Tandpasta Sensitive Instant Relief Whitening. Lavender SA, Petrou I, Heu R, Stranick MA, Cummins D, Kilpatrick-Liverman L, et al. Colgate Sensitive Pro Relief was found to achieve 91% dentin occlusion, compared to 67% for the stannous fluoride toothpaste. Thank you for your feedback. Mode of action studies on a new desensitizing dentifrice containing 8.0% arginine, a high cleaning calcium carbonate system and 1450 ppm fluoride. Colgate SENSITIVE PRO-Relief has been rebranded to Colgate SENSITIVE INSTANT Relief . Pro-Argin technology provides instant* and long-lasting, Oral Care Products | Colgate Professional. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. It has stannous fluoride as an active ingredient. Ashwini S, Swatika K, Kamala DN. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. Clinically proven lasting relief for 8 weeks. Lai et al. All authors read and approved the final manuscript. I am interested to hear you guys opinion and thought about it. 75 ml. For children 6-12 years of age, once a week or less frequently. 2017;9(4):e503. A study evaluating the efficacy of strontium acetate relative to arginine-based dentifrices was conducted by West et al. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. SHOULD A PATIENT CONTINUE USING Colgate SENSITIVE INSTANT Relief Repair & Prevent TOOTHPASTE ONCE THE DENTINE SENSITIVITY HAS GONE? These findings were similar to a previous study conducted by Schiff et al. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. Difference in effectiveness between strontium acetate and arginine-based toothpastes to relieve dentin hypersensitivity. Dentine hypersensitivity. Width 17 Height 5 Depth 3.8 Show More Payment & Refunds The main etiological factors are abrasion and erosion that may or may not be associated with gingival recession in DH. [9] stated in 2017 that arginine and strontium acetate-based desensitisers had equal clinical significance in reducing pain in DH and the other findings of the meta-analysis suggested that strontium acetate and Pro-argin should be compared for clinical efficacy immediately after topical application by independent health authorities. The permanent management of DH is being investigated with the remineralisation potential of bioactive agents in dentinal tubules. SJAZ has contributed to the conception, design, interpretation of results and critically revised the manuscript. BMC Oral Health Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a commercial sensitive toothpaste containing 2% potassium ion: an eight-week clinical study on Canadian adults. Vu Pham T, Anh Nguyen T. Clinical evaluation of the desensitizing efficacy of a paste containing 8% arginine and calcium carbonate. The relief from sensitivity offered by Colgate Sensitive Pro Relief is proven to last. Colgate Sensitive Pro Relief Whitening for improved stain removal. Plain bi-carb soda and coconut butter do a far better job at cleaning and desensitising. Nachar Sinus Rinse System, 4pcs Professional Baby Nasal Irrigator Portable Infant Nose Cleaner Quick Rinse Device All Natural Relief - BPA Free More Convenient. In addition, patients were educated regarding the cause of the disease for prevention and awareness of oral hygiene measures, brushing techniques, and dietary influences in DH. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. 2017;2017:2. J Clin Dent 20 (2009), special issue 17-22, 3. 5 Hines D et al. Written informed consent was obtained with a signed agreement plan to visit for six weeks at interim efficacy intervals of day three, week two, week four, and week six. No adverse events like gingival inflammation, bad taste, allergies, fluoride incompatibility, and dental or tongue stains were observed for all dentifrices. Pashley D. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. WHAT IS Colgate SENSITIVE INSTANT Relief Repair & Prevent? Significantly greater sensitivity reduction with twice - daily brushing compared to control toothpaste with potassium ions. J Clin Periodontol. Schulz KF, Altman DG, Moher D. CONSORT 2010 Statement: updated guidelines for reporting parallel group randomised trials. 2012;12(3):2208. The authors declare that they have no competing interests (financial and non-financial) related to the article. For more great Dental Care products like toothpaste and mouthwash, continue browsing online and buy in-store at B&M. Colgate Sensitive Instant Relief Toothpaste 75ml Product code: 326795 2.49 Subject to availability - visit your nearest store Colgate Sensitive Pro-Relief (Toothpaste): 1.9 out of 5 stars from 91 genuine reviews on Australia's largest opinion site ProductReview.com.au. For instant relief, apply directly to each sensitive tooth surface and massage for one minute, up to twice a day. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. SEALS & REPAIRS: Pro-Argin technology helps to seal and repair the sensitive areas of teeth. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . 2. Buy Colgate Sensitive Pro Relief and get the best deals at the lowest prices on eBay! Privacy Dentine tubule occlusion by novel bioactive glass-based toothpastes. Layer T, Hughes N. Evidence for the efficacy of an 8% strontium acetate dentifrice for instant and lasting relief of dentin hypersensitivity. Saba Arshad. J Dent. The outcomes are in concordance with the previous studies conducted by Layer and Hughes [26], Zang and Shaw [27], and Mason et al. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. J Clin Dent. 2019;46(12):11216. Delivering better oral health - An Evidence-based toolkit for prevention. J Clin Dent. Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. Amsterdam: Elsevier; 2015. p. 4576. 2018;9(3):3306. In addition, participants were asked to record the overall sensitivity of their day-to-day experience on provided VAS sheets reporting pain on brushing, taking hot or cold beverages, and rinsing with tap water for the six weeks of the study. 2018;75:1221. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, Matranga D, Matera F, Pizzo G. Evaluating the statistical methodology of randomized trials on dentin hypersensitivity management. 2017;71:18. The second null hypothesis was that mean scores for pain due to DH among different treatment groups for sustained relief remains the same, and it was considered to be rejected at a p value0.05. https://doi.org/10.17352/2394-8418.00003. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Customers also search toothpaste colgate sensitive colgate enamel colgate pro relief colgate pain relief All rights reserved. Moreover, there was no significant difference between dentifrices containing FCPS, Pro-argin, and 8% strontium acetate (p>0.05) on completion of trial after six weeks. (US). Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Colgate Sensitive Pro-relief Instant Relief. Am J Dent. This trial was registered in an ICMJE approved registry at https://clinicaltrials.gov/) under protocol Identifier: NCT04249336 [19] following the CONSORT guidelines [20] for parallel-group randomized trials after approval from the Institutional Review Board of Dow University of Health Sciences with reference no. 2017;59(4):4618. Colgate Sensitive Pro-Relief efektywnie i szybko znosi nadwraliwo zbw, zamyka kanaliki zbinowe w ktrych s zakoczenia nerww, dziki czemu blokuje bl. Am J Dent. 2008;29(8):1S-35S. In comparison, the Pro-argin can make mechanical barrier of calcium phosphate precipitates on exposed dentinal tubules up to 2m depth by the interaction of positively charged arginine, amino acids and type 1 collagen fibres [8]. All the treatment groups showed statistically significant improvement in DH with p<0.001 relative to baseline at all time points. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. Innehller slipmedel med ltt polerande effekt p flckar samt fluor som minskar risken fr karies. However, they also suggested further comparative evaluations of two dentifrices with large sample sizes as limited scientific evidence was found in previous studies [16]. Post-application changes on SCASS were observed after one minute, three days, two, four, and six weeks, subsequently. Lasting relief with 2x daily continued brushing. After six weeks, Pro-argin-based dentifrices showed greater clinical efficacy with mean scores (2.151.92) than other treatment arms for mechanical stimulated DH. 0. Tel: +381 (0)21 452-910, +381 (0)21 420-758. A meta-analysis by Matranga et al. Treatments provided to the patients were OTC dentifrices marketed with the claim of immediate pain relief in DH. Participants were asked to pick up the envelope from the box. The participants with self-reported sensitivity in teeth were clinically diagnosed with DH. Google Scholar. A total of 140 met the eligibility criteria with at least two sensitive teeth anterior to molars due to erosions or abrasions with or without an associated gingival recession. it is in a rubbish bin now. 2009;20(1):106. The sensitive toothpaste works in different ways to fight cavities, remove plaque, promote gum health and freshen breath. Colgate-Palmolive Company 2018. Participants were randomly allocated to four treatment arms and randomly assigned with OTC dentifrices having FCPS, Pro-argin, strontium acetate, and sodium fluoride (NaF) with an allocation ratio of 1:1:1:1. Bae J-H, Kim Y-K, Myung S-K. Desensitizing toothpaste versus placebo for dentin hypersensitivity: a systematic review and meta-analysis. 2017;457:2530. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (4.201.70) followed by strontium acetate (4.651.87) followed by FCPS (5.101.88) one minute after application. Oral Care Products | Colgate Professional, Colgate Toothpaste - Dentists & Patients | Colgate Professional, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste, Instantly* relieves dentine hypersensitivity, Long-lasting relief from the pain of sensitive teeth, Helps strengthen gums and prevent gum recession, Recommended fluoride level for caries protection (1450ppm). 2017;62(2):18691. The mean scores with repeated measures were statistically analysed at each time point for study outcomes. How to use When you recommend Colgate Sensitive Pro Relief, you can help your dentin hypersensitivity patients to enjoy a pain-free life, confident in the knowledge that youre providing a highly effective, evidence-based solution. Innehll Colgate Sensitive Instant Relief Enamel Repair r en fluortandkrm med Pro-Argin-teknologi som ger omedelbar smrtlindring vid ilningar i tnderna. The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. OTC dentifrices were applied and massaged gently with the applicator on at least two sensitive teeth per subject at two different sites, including cementoenamel junction and exposed dentinal surface, by the doctor in the office during the first visit. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Another study by Vu Pham and Anh Nguyen reported clinical improvement in DH by 38.9% on SCASS and 40.2% on VAS for mechanical stimulated DH immediately after application of Pro-argin [25]. Another . Based on the outcomes of previous systematic reviews and meta-analysis, the rationale of the present study was to substantiate the claim of immediate pain relief after one-minute application in DH by non-invasive surface application of OTC dentifrices containing Pro-arginin Colgate Sensitive Pro-Relief, and 8% strontium acetate in Sensodyne Rapid Action and other objective was the comparative evaluation of the clinical efficacy of three technologies, BAG-based FCPS in BioMinR F, Pro-argin, and 8% strontium acetate at efficacy intervals of day three, week two, four and six for sustained inhibition of painful stimulus provoking DH as all three are dentinal tubular occluding dentifrices. 2016;8:114. Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an 8-week clinical study. The New Colgate Sensitive Instant* Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. Effectiveness of dentifrices with new formulations for the treatment of dentin hypersensitivitya meta-analysis. Balevi B. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. Shrimathi S. Effect of BiominF, NovaminR, Argin and nanohydroxy particles containing dentifrices on dentine hypersensitivity and gingivitis among 3544 years aged population of Madurai district: a randomized controlled trial (RCT). Colgate Sensitive PRO-Relief Provides clinically proven, everyday protection from painful sensitivity. Springer Nature. With regular use, it creates a long-lasting protective barrier that acts as a seal against sensitivity. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. We provided oral hygiene instructions and ways of relieving their pain from DH to improve their quality of life. Not all desensitizing toothpastes perform equally well. [33] again reported a 54% clinical reduction in DH with Pro-argin in eight weeks clinical trial using SCASS. 1Intervention for Group A denotes BioMin F. 2Intervention for Group B denotes Colgate Sensitive Pro relief. With regular use, it reduces teeth sensitivity and helps to strengthen gums and prevent gum recession. A total of 128 participants completed the trial. 2010;21(2):568. Book Contemp Clin Dent. J Dent. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. Correspondence to Provides 24/7 sensitivity protection. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. 2018. Terms and Conditions, Compend Contin Educ Dent. Gently removes stains and helps restore the natural whiteness of your teeth. The current study outcomes showed significant decrease in pain scores of air-blasts and water jet stimulated DH with FCPS based dentifrices compared to Pro-argin and 8% strontium acetate after two, four, and six weeks subsequently, as depicted in Tables 4 and 5. Colgate Sensitive Pro-Relief toothpaste is a revolutionary and one-of-its kind remedy that can provide consumers suffering from Sensitivity the much needed instant and long lasting relief . Builds a protective barrier that acts like . Zinc helps strengthen gums and prevent gum recession a key cause of sensitivity1,2,3. J Evid Based Dent Pract. 2017;2017:2. Two double-blind randomized clinical studies by Nathoo et al. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. Colgate Sensitive Pro-Relief Complete Protection sensitivity toothpaste is clinically proven for instant and lasting relief from sensitivity pain. 2013;41:S317. For lasting relief and gum protection, apply twice daily using a sensitive toothbrush, making sure to brush all surfaces of teeth including sensitive areas. By using this website, you agree to our Pro-Argin technology can be found in Colgate Sensitive Pro Relief Toothpaste, sold as Colgate Sensitive Instant Relief in the UK and elmex Sensitive Professional in Europe. Google Scholar. Explore the videos and articles found on this page to assist in better oral care. Today's era of flourishing research in DH is based on incorporating bioactive ingredients in commercially available oral dentifrices that can induce deep intratubular remineralisation of dental hard tissues for permanent or long-term treatment purposes. When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. Colgate Sensitive Pro Relief Instant Relief, Plugging the channels that lead to sensitive tooth nerves to help relieve sensitivity. The loss of tooth enamel is the most common cause of tooth sensitivity and is not affected by cavities, gum disease, or other problems. This clinical trial has not included a run-in or washout period before the test phase due to time constraints and compliance of the potential participants. Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. PubMed Central All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. The first post-treatment measure of SCASS and VAS scores was obtained immediately after removing dentifrices from teeth. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. In addition, the frequency of participants diagnosed with DH using air blast stimulus was observed as 36.8% at the time of enrolment in the six-week clinical trial that was found consistent with findings of a survey report demonstrating 36.4% frequency of DH among adults in Karachi, Pakistan [24]. While FCPS in BioMin F can be the best possible treatment option for long-term management of DH in the form of OTC dentifrices. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. Learn more about caries in children from the resources provided on this page. It revealed an immediate improvement with strontium acetate more than Pro-argin on SCASS. Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. Gillam D, Hill R, Samueli A. Bioactive glasses in the management of dentine hypersensitivity: a review. Am J Dent. 6 Ipsos, Romania Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2-week trial, 545 respondents, 2015. 2015;42(2):13141. Thus, 128 participants completed the trial and were statistically analyzed for primary outcome measure of SCASS scores after lost to follow up (Fig. In our study, Pro-argin treatment revealed an immediate clinical reduction of 45.7% on SCASS, 56% on VAS used for mechanical stimuli, and 48.1% on VAS used for water jet stimuli in DH demonstrated in Tables 3, 5, and 6. Pessoa, Loretto et al. These outcomes were found in concordance with the previous controlled clinical trial conducted by Patel et al. Hu et al.